PPP1R9B
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- actin filament organization [IPI]
- calcium-mediated signaling [IMP]
- cell migration [ISO]
- cellular response to morphine [IMP]
- dendrite development [IMP]
- filopodium assembly [ISO]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [IMP]
- regulation of protein phosphorylation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
AKAP5
Gene Ontology Biological Process
- cellular protein complex disassembly [ISO]
- negative regulation of adenylate cyclase activity [ISO]
- negative regulation of ion transport [ISO]
- negative regulation of potassium ion transport [ISO]
- positive regulation of NFAT protein import into nucleus [ISO]
- positive regulation of adenylate cyclase activity [ISO]
- positive regulation of cAMP biosynthetic process [ISO]
- positive regulation of calcium ion transport into cytosol [ISO]
- positive regulation of dendrite morphogenesis [ISO]
- positive regulation of protein kinase A signaling [ISO]
- positive regulation of protein phosphorylation [ISO]
Gene Ontology Molecular Function- G-protein coupled receptor binding [ISO]
- GABA receptor binding [ISO]
- actin binding [ISO]
- adenylate cyclase binding [ISO]
- cadherin binding [ISO]
- kinase binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [ISO]
- protein kinase A regulatory subunit binding [ISO]
- protein kinase binding [ISO]
- protein phosphatase 2B binding [ISO]
- G-protein coupled receptor binding [ISO]
- GABA receptor binding [ISO]
- actin binding [ISO]
- adenylate cyclase binding [ISO]
- cadherin binding [ISO]
- kinase binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [ISO]
- protein kinase A regulatory subunit binding [ISO]
- protein kinase binding [ISO]
- protein phosphatase 2B binding [ISO]
Gene Ontology Cellular Component
- asymmetric synapse [ISO]
- basolateral plasma membrane [ISO]
- cytoplasm [ISO]
- dendrite membrane [ISO]
- dendritic shaft [ISO]
- dendritic spine [ISO]
- dendritic spine membrane [ISO]
- filopodium membrane [ISO]
- neuronal cell body [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- postsynaptic density [ISO]
- protein complex [ISO]
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.
Glutamatergic projections from the cortex and dopaminergic projections from the substantia nigra or ventral tegmental area synapse on dendritic spines of specific GABAergic medium spiny neurons (MSNs) in the striatum. Direct pathway MSNs (dMSNs) are positively coupled to protein kinase A (PKA) signaling and activation of these neurons enhance specific motor programs whereas indirect pathway MSNs (iMSNs) are negatively coupled ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
PPP1R9B AKAP5 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - |
Curated By
- BioGRID