BAIT
PPP1R9B
SPL, Spn, RP23-112C19.3
protein phosphatase 1, regulatory subunit 9B
GO Process (10)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- actin filament organization [IPI]
- calcium-mediated signaling [IMP]
- cell migration [ISO]
- cellular response to morphine [IMP]
- dendrite development [IMP]
- filopodium assembly [ISO]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [IMP]
- regulation of protein phosphorylation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RAB14
0610030G24Rik, 2810475J17Rik, A830021G03Rik, AI314285, AI649155, D030017L14Rik, RP23-186B18.6
RAB14, member RAS oncogene family
GO Process (11)
GO Function (6)
GO Component (22)
Gene Ontology Biological Process
- GTP catabolic process [IBA, ISO]
- Golgi to endosome transport [IMP]
- Rab protein signal transduction [IBA]
- apical protein localization [ISO]
- body fluid secretion [ISO]
- embryo development [IMP]
- endocytic recycling [ISO]
- fibroblast growth factor receptor signaling pathway [IMP]
- intracellular protein transport [IBA]
- phagolysosome assembly involved in apoptotic cell clearance [IBA]
- regulation of protein localization [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IBA]
- Golgi stack [ISO]
- alveolar lamellar body [ISO]
- apical plasma membrane [ISO]
- cell [IMP]
- cytoplasm [IMP]
- cytosol [ISO]
- early endosome [IBA, ISO]
- extracellular vesicular exosome [ISO]
- intracellular [IMP, ISO]
- intracellular membrane-bounded organelle [ISO]
- late endosome [ISO]
- lysosomal membrane [ISO]
- lysosome [ISO]
- nuclear outer membrane-endoplasmic reticulum membrane network [ISO]
- perinuclear region of cytoplasm [ISO]
- phagocytic vesicle [IBA, ISO]
- plasma membrane [ISO]
- recycling endosome [ISO]
- rough endoplasmic reticulum [ISO]
- trans-Golgi network transport vesicle [ISO]
- transport vesicle [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.
Glutamatergic projections from the cortex and dopaminergic projections from the substantia nigra or ventral tegmental area synapse on dendritic spines of specific GABAergic medium spiny neurons (MSNs) in the striatum. Direct pathway MSNs (dMSNs) are positively coupled to protein kinase A (PKA) signaling and activation of these neurons enhance specific motor programs whereas indirect pathway MSNs (iMSNs) are negatively coupled ... [more]
Proteomes Dec. 17, 2018; 6(4); [Pubmed: 30562941]
Throughput
- High Throughput
Curated By
- BioGRID