BAIT
CEBPA
DBPCEP
CCAAT/enhancer binding protein (C/EBP), alpha
GO Process (34)
GO Function (16)
GO Component (6)
Gene Ontology Biological Process
- acute-phase response [IEP]
- brown fat cell differentiation [ISO]
- cell differentiation [IEP]
- cell maturation [ISO]
- cellular response to lithium ion [ISO]
- cellular response to organic cyclic compound [ISO]
- cholesterol metabolic process [ISO]
- embryonic placenta development [ISO]
- fat cell differentiation [ISO]
- inner ear development [ISO]
- liver development [IEP, ISO]
- lung development [ISO]
- macrophage differentiation [ISO]
- mitochondrion organization [ISO]
- myeloid cell differentiation [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [IDA]
- organ regeneration [IEP]
- positive regulation of fat cell differentiation [IMP, ISO]
- positive regulation of osteoblast differentiation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- positive regulation of transcription from RNA polymerase III promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of cell proliferation [ISO]
- regulation of transcription from RNA polymerase II promoter [ISO]
- regulation of transcription, DNA-templated [IDA, ISO, TAS]
- response to glucocorticoid [IEP]
- response to nutrient [IEP]
- response to vitamin B2 [IEP]
- transcription from RNA polymerase II promoter [ISO]
- transcription, DNA-templated [ISO]
- urea cycle [ISO]
- white fat cell differentiation [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- HMG box domain binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- histone deacetylase binding [IPI]
- protein binding [IPI]
- protein complex binding [IDA]
- protein domain specific binding [IPI]
- protein heterodimerization activity [IDA, IPI]
- protein homodimerization activity [IDA, IPI, ISO]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
- DNA binding [IDA, ISO]
- HMG box domain binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- histone deacetylase binding [IPI]
- protein binding [IPI]
- protein complex binding [IDA]
- protein domain specific binding [IPI]
- protein heterodimerization activity [IDA, IPI]
- protein homodimerization activity [IDA, IPI, ISO]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
Gene Ontology Cellular Component
Rattus norvegicus
PREY
HSD17B12
2610510O05Rik, AI172963, KIK-I, Kik1, RP23-41P22.3
hydroxysteroid (17-beta) dehydrogenase 12
GO Process (2)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.
C/EBPa and C/EBPb are transcription factors with tissue specific expression regulating several important cellular processes. They work by recruiting protein complexes to a common DNA recognition motif and both are able to compensate each other's absence in many cell types, thus showing functional redundancy. They also play distinct roles in specific cellular pathways and their abnormal functioning gives raise to ... [more]
Biochim Biophys Acta Gen Subj Feb. 01, 2017; 1861(2);467-476 [Pubmed: 27746211]
Throughput
- High Throughput
Curated By
- BioGRID