BAIT
THRB
C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
thyroid hormone receptor, beta
GO Process (4)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BRD8
SMAP, SMAP2, p120
bromodomain containing 8
GO Process (8)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- cell surface receptor signaling pathway [TAS]
- chromatin organization [TAS]
- histone H2A acetylation [IDA]
- histone H4 acetylation [IDA]
- intracellular receptor signaling pathway [TAS]
- regulation of transcription from RNA polymerase II promoter [TAS]
- regulation of transcription, DNA-templated [NAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein.
The thyroid hormone receptor (TR) regulates the expression of target genes upon binding to triiodothyronine (T3) response elements. In the presence of T3, the TR recruits coactivating proteins that both modulate and integrate the ligand response. We report here the cloning of a novel protein using the TR ligand-binding domain as bait in the yeast two-hybrid system. Analysis of a ... [more]
J. Biol. Chem. Nov. 21, 1997; 272(47);29834-41 [Pubmed: 9368056]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID