BAIT

BAP1

HUCEP-13, UCHL2, hucep-6
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
UPS Project
Homo sapiens
PREY

IPO5

IMB3, KPNB3, Pse1, RANBP5, imp5, RP11-72J7.1
importin 5
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma.

Sime W, Niu Q, Abassi Y, Masoumi KC, Zarrizi R, Kohler JB, Kjellstroem S, Lasorsa VA, Capasso M, Fu H, Massoumi R

BRCA1-associated protein 1 (BAP1) is a nuclear deubiquitinating enzyme that is associated with multiprotein complexes that regulate key cellular pathways, including cell cycle, cellular differentiation, cell death, and the DNA damage response. In this study, we found that the reduced expression of BAP1 pro6motes the survival of neuroblastoma cells, and restoring the levels of BAP1 in these cells facilitated a ... [more]

Cell Death Dis Dec. 01, 2017; 9(5);458 [Pubmed: 29686263]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
BAP1 IPO5
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High1.48BioGRID
423116
BAP1 IPO5
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High-BioGRID
3466963

Curated By

  • BioGRID