BAIT
FCGR2B
CD32, CD32B, FCG2, FCGR2, IGFR2, RP11-474I16.2
Fc fragment of IgG, low affinity IIb, receptor (CD32)
GO Process (3)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GAB1
GRB2-associated binding protein 1
GO Process (8)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- cell proliferation [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- innate immune response [TAS]
- insulin receptor signaling pathway [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- phosphatidylinositol-mediated signaling [TAS]
Gene Ontology Molecular Function
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Co-clustering of Fcgamma and B cell receptors induces dephosphorylation of the Grb2-associated binder 1 docking protein.
The immunoreceptor tyrosine-based inhibitory motif (ITIM) of human type IIb Fcgamma receptor (FcgammaRIIb) is phosphorylated on its tyrosine upon co-clustering with the B cell receptor (BCR). The phosphorylated ITIM (p-ITIM) binds to the SH2 domains of polyphosphoinositol 5-phosphatase (SHIP) and the tyrosine phosphatase, SHP-2. We investigated the involvement of the molecular complex composed of the phosphorylated SHIP and FcgammaRIIb in ... [more]
Eur. J. Biochem. Jul. 01, 2001; 268(14);3898-906 [Pubmed: 11453982]
Throughput
- Low Throughput
Curated By
- BioGRID