BAIT
GLP1R
glucagon-like peptide 1 receptor
GO Process (6)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC27A4
BB144259, FATP4, RP23-457B12.1
solute carrier family 27 (fatty acid transporter), member 4
GO Process (8)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- fatty acid metabolic process [IMP]
- long-chain fatty acid import [ISO]
- long-chain fatty acid metabolic process [IDA, ISO, TAS]
- long-chain fatty acid transport [IMP]
- medium-chain fatty acid transport [IDA, IGI]
- skin development [IMP]
- very long-chain fatty acid catabolic process [IDA]
- very long-chain fatty acid metabolic process [IDA, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells.
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that regulates glucose homeostasis. Because of their direct stimulation of insulin secretion from pancreatic β cells, GLP-1 receptor (GLP-1R) agonists are now important therapeutic options for the treatment of type 2 diabetes. To better understand the mechanisms that control the insulinotropic actions of GLP-1, affinity purification and mass spectrometry (AP-MS) were employed to ... [more]
Mol. Cell Proteomics Nov. 01, 2014; 13(11);3049-62 [Pubmed: 25044020]
Throughput
- High Throughput
Curated By
- BioGRID