PREY

CTNND1

CAS, CTNND, P120CAS, P120CTN, p120, p120(CAS), p120(CTN)
catenin (cadherin-associated protein), delta 1
Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

The P2Y2 Receptor Interacts with VE-Cadherin and VEGF Receptor-2 to Regulate Rac1 Activity in Endothelial Cells.

Liao Z, Cao C, Wang J, Huxley VH, Baker O, Weisman GA, Erb L

Vascular endothelial cadherin (VE-cadherin) mediates homophylic adhesion between endothelial cells and is an important regulator of angiogenesis, blood vessel permeability and leukocyte trafficking. Rac1, a member of the Rho family of GTPases, controls VE-cadherin adhesion by acting downstream of several growth factors, including angiopoietin-1 and vascular endothelial growth factor (VEGF). Here we show that UTP-induced activation of the Gq protein-coupled ... [more]

J Biomed Sci Eng Dec. 01, 2014; 7(14);1105-1121 [Pubmed: 25657827]

Throughput

  • Low Throughput

Curated By

  • BioGRID