BAIT
TRPC1
Mtrp1, Trp1, Trrp1
transient receptor potential cation channel, subfamily C, member 1
GO Process (6)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ENKUR
4933434I06Rik, AU016229, RP23-442K5.1
enkurin, TRPC channel interacting protein
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Enkurin is a novel calmodulin and TRPC channel binding protein in sperm.
The TRPC cation channel family has been implicated in receptor- or phospholipase C (PLC)-mediated Ca2+ entry into animal cells. These channels are present in mammalian sperm and are assigned a role in ZP3-evoked Ca2+ influx that drives acrosome reactions. However, the mechanisms controlling channel activity and coupling Ca2+ entry through these channels to cellular responses are not well understood. A ... [more]
Dev. Biol. Oct. 15, 2004; 274(2);426-35 [Pubmed: 15385169]
Throughput
- Low Throughput
Curated By
- BioGRID