BAIT

HORMAD2

CT46.2
HORMA domain containing 2
GO Process (2)
GO Function (0)
GO Component (2)

Gene Ontology Cellular Component

Homo sapiens
PREY

HORMAD2

CT46.2
HORMA domain containing 2
GO Process (2)
GO Function (0)
GO Component (2)

Gene Ontology Cellular Component

Homo sapiens

Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

A conserved filamentous assembly underlies the structure of the meiotic chromosome axis.

West AM, Rosenberg SC, Ur SN, Lehmer MK, Ye Q, Hagemann G, Caballero I, Uson I, MacQueen AJ, Herzog F, Corbett KD

The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are highly diverged. Here, we show that 'axis core proteins' from budding yeast (Red1), mammals (SYCP2/SYCP3), and plants (ASY3/ASY4) are evolutionarily related and play equivalent roles in chromosome axis assembly. We first identify 'closure motifs' in each complex that ... [more]

Elife Jan. 18, 2019; 8(); [Pubmed: 30657449]

Throughput

  • Low Throughput

Curated By

  • BioGRID