BAIT
TIAM1
T-cell lymphoma invasion and metastasis 1
GO Process (10)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- Rac protein signal transduction [IMP]
- apoptotic signaling pathway [TAS]
- cell migration [IMP]
- cell-matrix adhesion [IMP]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of Rac GTPase activity [IMP]
- positive regulation of Rho GTPase activity [TAS]
- positive regulation of apoptotic process [TAS]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ZKSCAN4
P1P373C6, ZNF307, ZNF427, ZSCAN36, p373c6.1
zinc finger with KRAB and SCAN domains 4
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Histone methyltransferase SETDB1 promotes cells proliferation and migration by interacting withTiam1 in hepatocellular carcinoma.
SETDB1 is a histone H3K9 methyltransferase, which plays a significant role in the occurrence and progression of tumors. Previous studies have confirmed that T-lymphom invasion and metastasis gene (Tiam1) is a protein associated with the metastasis of hepatocellular carcinoma (HCC); however, we have not yet been successful in elucidating the specific mechanism of HCC.Yeast two-hybrid test was conducted to screen ... [more]
BMC Cancer May. 08, 2018; 18(1);539 [Pubmed: 29739365]
Throughput
- High Throughput
Additional Notes
- Source of TIAM1 not clear
Curated By
- BioGRID