PREY

ATP6V1F

1110004G16Rik
ATPase, H+ transporting, lysosomal V1 subunit F
GO Process (2)
GO Function (1)
GO Component (3)
Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation.

Merkulova M, Paunescu TG, Azroyan A, Marshansky V, Breton S, Brown D

V-ATPases (H(+) ATPases) are multisubunit, ATP-dependent proton pumps that regulate pH homeostasis in virtually all eukaryotes. They are involved in key cell biological processes including vesicle trafficking, endosomal pH sensing, membrane fusion and intracellular signaling. They also have critical systemic roles in renal acid excretion and blood pH balance, male fertility, bone remodeling, synaptic transmission, olfaction and hearing. Furthermore, V-ATPase ... [more]

Sci Rep Oct. 07, 2015; 5();14827 [Pubmed: 26442671]

Throughput

  • High Throughput

Curated By

  • BioGRID