BAIT
DTD1
C20orf88, DUE-B, DUEB, HARS2, bA379J5.3, bA555E18.1, pqn-68
D-tyrosyl-tRNA deacylase 1
GO Process (2)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
DTD1
C20orf88, DUE-B, DUEB, HARS2, bA379J5.3, bA555E18.1, pqn-68
D-tyrosyl-tRNA deacylase 1
GO Process (2)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Protein phosphatase 2A and Cdc7 kinase regulate the DNA unwinding element-binding protein in replication initiation.
The DNA unwinding element (DUE)-binding protein (DUE-B) binds to replication origins coordinately with the minichromosome maintenance (MCM) helicase and the helicase activator Cdc45 in vivo, and loads Cdc45 onto chromatin in Xenopus egg extracts. Human DUE-B also retains the aminoacyl-tRNA proofreading function of its shorter orthologs in lower organisms. Here we report that phosphorylation of the DUE-B unstructured C-terminal domain ... [more]
J. Biol. Chem. Dec. 26, 2014; 289(52);35987-6000 [Pubmed: 25258324]
Throughput
- Low Throughput
Curated By
- BioGRID