BAIT
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
GO Process (4)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
FDPS
Ac2-125, FPS
farnesyl diphosphate synthase
GO Process (12)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- cellular response to fatty acid [IEP]
- cholesterol biosynthetic process [TAS]
- farnesyl diphosphate biosynthetic process [IDA]
- isoprenoid biosynthetic process [IDA]
- male gonad development [IEP]
- positive regulation of cell growth involved in cardiac muscle cell development [IMP]
- positive regulation of cholesterol biosynthetic process [IMP]
- response to cholesterol [IEP]
- response to drug [IEP]
- response to peptide hormone [IEP]
- response to testosterone [IEP]
- spermatogenesis [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry.
The heterotrimeric enzyme AMP-activated protein kinase (AMPK) is a major metabolic factor that regulates the homeostasis of cellular energy. In particular, AMPK mediates the insulin resistance that is associated with type 2 diabetes. Generally, cellular processes require tight regulation of protein kinases, which is effected through their formation of complex with other proteins and substrates. Despite their critical function in ... [more]
Sci Rep Mar. 15, 2014; 4(0);4376 [Pubmed: 24625528]
Throughput
- High Throughput
Curated By
- BioGRID