BAIT
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
GO Process (4)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
LDHA
Ldh1
lactate dehydrogenase A
GO Process (15)
GO Function (6)
GO Component (6)
Gene Ontology Biological Process
- NAD metabolic process [IDA]
- cellular response to extracellular stimulus [ISO]
- lactate metabolic process [IDA]
- oxidation-reduction process [ISO]
- positive regulation of apoptotic process [IDA]
- post-embryonic organ development [IEP]
- response to cAMP [IEP]
- response to drug [IEP]
- response to estrogen [IEP]
- response to glucose [IEP]
- response to hydrogen peroxide [IEP]
- response to hypoxia [IEP]
- response to nutrient [IEP]
- response to organic cyclic compound [IEP]
- substantia nigra development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry.
The heterotrimeric enzyme AMP-activated protein kinase (AMPK) is a major metabolic factor that regulates the homeostasis of cellular energy. In particular, AMPK mediates the insulin resistance that is associated with type 2 diabetes. Generally, cellular processes require tight regulation of protein kinases, which is effected through their formation of complex with other proteins and substrates. Despite their critical function in ... [more]
Sci Rep Mar. 15, 2014; 4(0);4376 [Pubmed: 24625528]
Throughput
- High Throughput
Curated By
- BioGRID