BAIT
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
GO Process (4)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
MAP1B
Mtap1b
microtubule-associated protein 1B
GO Process (30)
GO Function (5)
GO Component (16)
Gene Ontology Biological Process
- axon extension [ISO]
- axonogenesis [ISO]
- cellular process [ISO]
- cellular response to growth factor stimulus [IEP]
- cellular response to peptide hormone stimulus [IEP]
- dendrite development [ISO]
- developmental maturation [IEP]
- establishment of monopolar cell polarity [ISO]
- induction of synaptic plasticity by chemical substance [IEP]
- microtubule bundle formation [IDA, ISO]
- mitochondrion transport along microtubule [ISO]
- negative regulation of intracellular transport [ISO]
- negative regulation of microtubule depolymerization [IDA]
- nervous system development [IEP]
- neuron development [IEP]
- peripheral nervous system axon regeneration [IEP]
- positive regulation of axon extension [IMP, ISO]
- positive regulation of microtubule polymerization [IDA]
- positive regulation of neuron differentiation [IMP]
- response to axon injury [IEP]
- response to carbohydrate [IEP]
- response to drug [IEP]
- response to estradiol [IEP]
- response to inorganic substance [IEP]
- response to insecticide [IEP]
- response to mechanical stimulus [IEP]
- response to nutrient levels [IEP]
- response to vitamin A [IEP]
- response to wounding [IEP]
- synapse assembly [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon [IDA]
- cell [ISO]
- cytoplasm [ISO]
- cytoskeleton [IDA]
- cytosol [ISO]
- dendrite [IDA]
- growth cone [IDA]
- intracellular [ISO]
- microtubule associated complex [IDA]
- neuronal cell body [IDA]
- neuronal postsynaptic density [ISO]
- perikaryon [IDA]
- perinuclear region of cytoplasm [IDA]
- photoreceptor outer segment [ISO]
- plasma membrane [IDA, ISO]
- postsynaptic density [IDA, ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry.
The heterotrimeric enzyme AMP-activated protein kinase (AMPK) is a major metabolic factor that regulates the homeostasis of cellular energy. In particular, AMPK mediates the insulin resistance that is associated with type 2 diabetes. Generally, cellular processes require tight regulation of protein kinases, which is effected through their formation of complex with other proteins and substrates. Despite their critical function in ... [more]
Sci Rep Mar. 15, 2014; 4(0);4376 [Pubmed: 24625528]
Throughput
- High Throughput
Curated By
- BioGRID