BAIT

NAV2

5330421F07Rik, AU067780, BQ960892, HELAD1, POMFIL2, RAINB1, RAINB2, Unc53H2, mKIAA3015, mCG_145366
neuron navigator 2
Mus musculus
PREY

ZNF236

ZNF236A, ZNF236B
zinc finger protein 236
GO Process (1)
GO Function (0)
GO Component (0)

Gene Ontology Biological Process

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

14-3-3ε and NAV2 interact to regulate neurite outgrowth and axon elongation.

Marzinke MA, Mavencamp T, Duratinsky J, Clagett-Dame M

Neuron navigator 2 (NAV2) is required for all-trans retinoic acid (atRA) to induce neurite outgrowth in human neuroblastoma cells. Further, ectopic overexpression of full-length human NAV2 rescues an axonal elongation defect in the Caenorhabditis elegans unc-53 (NAV2 ortholog) mutant. Using a region of NAV2 that independently associates with the cytoskeleton as bait in a yeast-two-hybrid screen, 14-3-3ε was identified as ... [more]

Arch. Biochem. Biophys. Dec. 01, 2013; 540(1-2);94-100 [Pubmed: 24161943]

Throughput

  • High Throughput

Curated By

  • BioGRID