Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

A novel GTP-binding protein-adaptor protein complex responsible for export of Vangl2 from the trans Golgi network.

Guo Y, Zanetti G, Schekman R

Planar cell polarity (PCP) requires the asymmetric sorting of distinct signaling receptors to distal and proximal surfaces of polarized epithelial cells. We have examined the transport of one PCP signaling protein, Vangl2, from the trans Golgi network (TGN) in mammalian cells. Using siRNA knockdown experiments, we find that the GTP-binding protein, Arfrp1, and the clathrin adaptor complex 1 (AP-1) are ... [more]

Elife Jan. 08, 2013; 2();e00160 [Pubmed: 23326640]

Throughput

  • Low Throughput

Curated By

  • BioGRID