BBS4
Gene Ontology Biological Process
- Kupffer's vesicle development [IGI, IMP]
- axis elongation involved in somitogenesis [IGI, IMP]
- cilium assembly [IMP]
- convergent extension [IGI, IMP]
- convergent extension involved in gastrulation [IMP]
- determination of heart left/right asymmetry [IGI, IMP]
- determination of left/right symmetry [IGI]
- gastrulation [IMP]
- heart looping [IMP]
- intracellular transport [IMP]
- melanosome transport [IGI, IMP]
- photoreceptor cell outer segment organization [IGI, IMP]
- pigment granule aggregation in cell center [IMP]
- regulation of Notch signaling pathway [IGI, IMP]
- rhodopsin metabolic process [IGI, IMP]
Gene Ontology Cellular Component
BBS7
Gene Ontology Biological Process
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A BBSome subunit links ciliogenesis, microtubule stability, and acetylation.
Primary cilium dysfunction affects the development and homeostasis of many organs in Bardet-Biedl syndrome (BBS). We recently showed that seven highly conserved BBS proteins form a stable complex, the BBSome, that functions in membrane trafficking to and inside the primary cilium. We have now discovered a BBSome subunit that we named BBIP10. Similar to other BBSome subunits, BBIP10 localizes to ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| BBS4 BBS7 | Co-purification Co-purification An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps. | Low | - | BioGRID | - |
Curated By
- BioGRID