BAIT
DSCAM
4932410A21Rik
Down syndrome cell adhesion molecule
GO Process (7)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- dendrite morphogenesis [IMP]
- dendrite self-avoidance [IMP]
- locomotory behavior [IMP]
- negative regulation of cell adhesion [IMP]
- positive regulation of axon extension involved in axon guidance [IDA, ISO]
- positive regulation of phosphorylation [ISO]
- post-embryonic retina morphogenesis in camera-type eye [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NCAM1
CD56, E-NCAM, NCAM-1, Ncam
neural cell adhesion molecule 1
GO Process (16)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- aging [ISO]
- cell surface receptor signaling pathway [IDA]
- homotypic cell-cell adhesion [IMP]
- learning or memory [ISO]
- multicellular organismal response to stress [ISO]
- negative regulation of cell death [ISO]
- neuron development [ISO]
- neuron projection development [IGI]
- positive regulation of calcium-mediated signaling [IDA]
- positive regulation of cardiac muscle cell proliferation [ISO]
- regulation of exocyst assembly [IMP]
- regulation of sensory perception of pain [ISO]
- response to cocaine [ISO]
- response to fluoxetine [ISO]
- response to lead ion [ISO]
- thalamus development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.
In the inner plexiform layer (IPL) of the mouse retina, ~70 neuronal subtypes organize their neurites into an intricate laminar structure that underlies visual processing. To find recognition proteins involved in lamination, we utilized microarray data from 13 subtypes to identify differentially-expressed extracellular proteins and performed a high-throughput biochemical screen. We identified ~50 previously-unknown receptor-ligand pairs, including new interactions among ... [more]
Elife Dec. 04, 2015; 4(0); [Pubmed: 26633812]
Throughput
- High Throughput
Additional Notes
- ELISA-based HTP assay
Curated By
- BioGRID