BAIT
NRP2
1110048P06Rik, Np-2, Np2, Npn-2, Npn2, RP23-149A5.1
neuropilin 2
GO Process (13)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- axon extension involved in axon guidance [IMP]
- axon guidance [IMP]
- gonadotrophin-releasing hormone neuronal migration to the hypothalamus [IMP]
- heart development [IGI]
- negative chemotaxis [IGI, IMP]
- nerve development [IMP]
- neural crest cell migration [IMP]
- neuron migration [IMP]
- semaphorin-plexin signaling pathway [IDA]
- semaphorin-plexin signaling pathway involved in neuron projection guidance [IMP]
- sympathetic ganglion development [IMP]
- sympathetic neuron projection extension [IMP]
- sympathetic neuron projection guidance [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon [IDA]
- plasma membrane [IC]
Mus musculus
PREY
SEMA4B
SemC, Semac, mKIAA1745
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
GO Process (0)
GO Function (1)
GO Component (4)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.
In the inner plexiform layer (IPL) of the mouse retina, ~70 neuronal subtypes organize their neurites into an intricate laminar structure that underlies visual processing. To find recognition proteins involved in lamination, we utilized microarray data from 13 subtypes to identify differentially-expressed extracellular proteins and performed a high-throughput biochemical screen. We identified ~50 previously-unknown receptor-ligand pairs, including new interactions among ... [more]
Elife Dec. 04, 2015; 4(0); [Pubmed: 26633812]
Throughput
- High Throughput
Additional Notes
- ELISA-based HTP assay
Curated By
- BioGRID