PLXNA4
Gene Ontology Biological Process
- anterior commissure morphogenesis [IMP]
- axon guidance [IMP]
- chemorepulsion of branchiomotor axon [IMP]
- cranial nerve morphogenesis [IMP]
- facial nerve morphogenesis [IMP]
- glossopharyngeal nerve morphogenesis [IMP]
- nervous system development [IGI]
- neuron projection morphogenesis [IMP]
- postganglionic parasympathetic nervous system development [IMP]
- regulation of axon extension involved in axon guidance [IMP]
- regulation of negative chemotaxis [IMP]
- semaphorin-plexin signaling pathway [IGI, IMP]
- sympathetic nervous system development [IMP]
- trigeminal nerve morphogenesis [IMP]
- vagus nerve morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SEMA6A
Gene Ontology Biological Process
Gene Ontology Molecular Function
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.
In the inner plexiform layer (IPL) of the mouse retina, ~70 neuronal subtypes organize their neurites into an intricate laminar structure that underlies visual processing. To find recognition proteins involved in lamination, we utilized microarray data from 13 subtypes to identify differentially-expressed extracellular proteins and performed a high-throughput biochemical screen. We identified ~50 previously-unknown receptor-ligand pairs, including new interactions among ... [more]
Throughput
- High Throughput
Additional Notes
- ELISA-based HTP assay
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
SEMA6A PLXNA4 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.961 | BioGRID | 2683828 |
Curated By
- BioGRID