BAIT
PLXNB1
2900002G15Rik, AU042020, mKIAA0407
plexin B1
GO Process (11)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- negative regulation of cell adhesion [ISO]
- negative regulation of osteoblast proliferation [IMP]
- neuron projection morphogenesis [IMP]
- ossification involved in bone maturation [IMP]
- positive regulation of Rho GTPase activity [IMP]
- positive regulation of axonogenesis [IGI]
- positive regulation of phosphatidylinositol 3-kinase signaling [IMP]
- regulation of cell shape [IMP, ISO]
- regulation of cytoskeleton organization [ISO]
- semaphorin-plexin signaling pathway [IMP, ISO]
- semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SEMA4G
AI507908, AW554132
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.
In the inner plexiform layer (IPL) of the mouse retina, ~70 neuronal subtypes organize their neurites into an intricate laminar structure that underlies visual processing. To find recognition proteins involved in lamination, we utilized microarray data from 13 subtypes to identify differentially-expressed extracellular proteins and performed a high-throughput biochemical screen. We identified ~50 previously-unknown receptor-ligand pairs, including new interactions among ... [more]
Elife Dec. 04, 2015; 4(0); [Pubmed: 26633812]
Throughput
- High Throughput
Additional Notes
- ELISA-based HTP assay
Curated By
- BioGRID