BAIT
PLXNB2
Debt, plexin-B2
plexin B2
GO Process (9)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- brain development [IMP]
- neural tube closure [IMP]
- neuroblast proliferation [IMP]
- positive regulation of axonogenesis [IGI]
- regulation of Rho GTPase activity [IMP]
- regulation of cell shape [IMP]
- regulation of neuron migration [IMP]
- regulation of protein phosphorylation [IMP]
- semaphorin-plexin signaling pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SEMA4C
AI426163, Semacl1, Semaf, Semai, mKIAA1739
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
GO Process (6)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.
In the inner plexiform layer (IPL) of the mouse retina, ~70 neuronal subtypes organize their neurites into an intricate laminar structure that underlies visual processing. To find recognition proteins involved in lamination, we utilized microarray data from 13 subtypes to identify differentially-expressed extracellular proteins and performed a high-throughput biochemical screen. We identified ~50 previously-unknown receptor-ligand pairs, including new interactions among ... [more]
Elife Dec. 04, 2015; 4(0); [Pubmed: 26633812]
Throughput
- High Throughput
Additional Notes
- ELISA-based HTP assay
Curated By
- BioGRID