BAIT
PLXNB3
AI451018, Plxn6, RP23-373N8.3
plexin B3
GO Process (8)
GO Function (4)
GO Component (0)
Gene Ontology Biological Process
- cell chemotaxis [ISO]
- negative regulation of GTPase activity [ISO]
- negative regulation of cell adhesion [ISO]
- negative regulation of cell migration [ISO]
- negative regulation of lamellipodium assembly [ISO]
- positive chemotaxis [ISO]
- positive regulation of endothelial cell proliferation [ISO]
- semaphorin-plexin signaling pathway [ISO]
Gene Ontology Molecular Function
Mus musculus
PREY
SEMA4F
sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
GO Process (3)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.
In the inner plexiform layer (IPL) of the mouse retina, ~70 neuronal subtypes organize their neurites into an intricate laminar structure that underlies visual processing. To find recognition proteins involved in lamination, we utilized microarray data from 13 subtypes to identify differentially-expressed extracellular proteins and performed a high-throughput biochemical screen. We identified ~50 previously-unknown receptor-ligand pairs, including new interactions among ... [more]
Elife Dec. 04, 2015; 4(0); [Pubmed: 26633812]
Throughput
- High Throughput
Additional Notes
- ELISA-based HTP assay
Curated By
- BioGRID