GLRB
Gene Ontology Biological Process
- acrosome reaction [ISO]
- adult walking behavior [ISO]
- chloride transmembrane transport [ISO, ISS]
- ion transmembrane transport [IDA, ISS, TAS]
- ion transport [ISO, ISS]
- nervous system development [ISO, ISS]
- neuromuscular process [ISO]
- neuropeptide signaling pathway [ISO, ISS]
- protein heterooligomerization [IDA]
- regulation of membrane potential [ISO]
- righting reflex [ISO]
- startle response [ISO, ISS]
- synaptic transmission [ISO, ISS, TAS]
- synaptic transmission, glycinergic [IDA, ISO]
- visual perception [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PFN1
Gene Ontology Biological Process
- actin polymerization or depolymerization [TAS]
- cellular response to growth factor stimulus [IEP]
- negative regulation of actin filament bundle assembly [ISO]
- negative regulation of actin filament polymerization [ISO]
- negative regulation of stress fiber assembly [ISO]
- neural tube closure [ISO]
- positive regulation of ATPase activity [ISO]
- positive regulation of DNA metabolic process [IDA]
- positive regulation of actin filament polymerization [ISO]
- positive regulation of epithelial cell migration [ISO]
- positive regulation of ruffle assembly [ISO]
- positive regulation of stress fiber assembly [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of viral transcription [IMP]
- regulation of transcription from RNA polymerase II promoter [ISO]
- response to organic substance [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system.
Gephyrin is an essential component of the postsynaptic cortical protein network of inhibitory synapses. Gephyrin-based scaffolds participate in the assembly as well as the dynamics of receptor clusters by connecting the cytoplasmic domains of glycine and GABA(A) receptor polypeptides to two cytoskeletal systems, microtubules and microfilaments. Although there is evidence for a physical linkage between gephyrin and microtubules, the interaction ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID