EED
Gene Ontology Biological Process
Gene Ontology Molecular Function
TGS1
Gene Ontology Biological Process
- 7-methylguanosine cap hypermethylation [IDA]
- RNA metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- gene expression [TAS]
- ncRNA metabolic process [TAS]
- ribonucleoprotein complex biogenesis [IC]
- ribonucleoprotein complex import into nucleus [IC]
- small molecule metabolic process [TAS]
- spliceosomal snRNP assembly [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Different isoforms of PRIP-interacting protein with methyltransferase domain/trimethylguanosine synthase localizes to the cytoplasm and nucleus.
A protein family including the recently identified PIMT/Tgs1 (PRIP-interacting protein with methyltransferase domain/trimethylguanosine synthase) was identified by searching databases for homologues of a newly identified Drosophila protein with RNA-binding activity and methyltransferase domain. Antibodies raised against a short peptide of the mammalian homologue show a 90-kDa isoform expressed specifically in rat brain and testis and a 55-kDa form expressed ubiquitously. ... [more]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID