BAIT

CHTF18

C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, Ctf18, RUVBL, LA16c-321D2.4
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
GO Process (0)
GO Function (0)
GO Component (3)

Gene Ontology Cellular Component

Homo sapiens
PREY

HSPA4

APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY
heat shock 70kDa protein 4
GO Process (3)
GO Function (1)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

The alternative Ctf18-Dcc1-Ctf8-replication factor C complex required for sister chromatid cohesion loads proliferating cell nuclear antigen onto DNA.

Bermudez VP, Maniwa Y, Tappin I, Ozato K, Yokomori K, Hurwitz J

The linkage of sister chromatids after DNA replication ensures the faithful inheritance of chromosomes by daughter cells. In budding yeast, the establishment of sister chromatid cohesion requires Ctf8, Dcc1, and Ctf18, a homologue of the p140 subunit of the replication factor C (RFC). In this report we demonstrate that in 293T cells, Flag-tagged Ctf18 forms a seven-subunit cohesion-RFC complex comprised ... [more]

Proc. Natl. Acad. Sci. U.S.A. Sep. 02, 2003; 100(18);10237-42 [Pubmed: 12930902]

Throughput

  • Low Throughput

Curated By

  • BioGRID