BAIT

TNPO2

IPO3, KPNB2B, TRN2
transportin 2
GO Process (0)
GO Function (2)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens
PREY

A1CF

ACF, ACF64, ACF65, APOBEC1CF, ASP, RP11-564C4.2
APOBEC1 complementation factor
GO Process (4)
GO Function (4)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling.

Blanc V, Kennedy S, Davidson NO

C to U editing of the nuclear apolipoprotein B (apoB) transcript is mediated by a core enzyme containing a catalytic deaminase, apobec-1, and an RNA binding subunit, apobec-1 complementation factor (ACF). ACF expression is predominantly nuclear, including mutant proteins with deletions of a putative nuclear localization signal. We have now identified a novel 41-residue motif (ANS) in the auxiliary domain ... [more]

J. Biol. Chem. Oct. 17, 2003; 278(42);41198-204 [Pubmed: 12896982]

Throughput

  • Low Throughput

Curated By

  • BioGRID