BAIT
TGOLN2
TGN38, TGN46, TGN48, TGN51, TTGN2
trans-golgi network protein 2
GO Process (0)
GO Function (1)
GO Component (4)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC25A10
DIC
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
GO Process (11)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- carbohydrate metabolic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- dicarboxylic acid transport [TAS]
- gluconeogenesis [TAS]
- glucose metabolic process [TAS]
- ion transport [TAS]
- small molecule metabolic process [TAS]
- sulfide oxidation, using sulfide:quinone oxidoreductase [TAS]
- sulfur amino acid catabolic process [TAS]
- sulfur amino acid metabolic process [TAS]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
Protein-protein interactions govern almost all cellular functions. These complex networks of stable and transient associations can be mapped by affinity purification mass spectrometry (AP-MS) and complementary proximity-based labeling methods such as BioID. To exploit the advantages of both strategies, we here design and optimize an integrated approach combining AP-MS and BioID in a single construct, which we term MAC-tag. We ... [more]
Nat Commun Dec. 22, 2017; 9(1);1188 [Pubmed: 29568061]
Throughput
- High Throughput
Curated By
- BioGRID