COX4I1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
COX15
Gene Ontology Biological Process
- cellular respiration [IC]
- heme a biosynthetic process [IGI]
- heme biosynthetic process [TAS]
- hydrogen ion transmembrane transport [IGI, TAS]
- mitochondrial electron transport, cytochrome c to oxygen [IC]
- oxidation-reduction process [TAS]
- porphyrin-containing compound metabolic process [TAS]
- respiratory chain complex IV assembly [IMP]
- respiratory gaseous exchange [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
Protein-protein interactions govern almost all cellular functions. These complex networks of stable and transient associations can be mapped by affinity purification mass spectrometry (AP-MS) and complementary proximity-based labeling methods such as BioID. To exploit the advantages of both strategies, we here design and optimize an integrated approach combining AP-MS and BioID in a single construct, which we term MAC-tag. We ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| COX15 COX4I1 | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 1 | BioGRID | 2849677 | |
| COX4I1 COX15 | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 500 | BioGRID | 2983998 |
Curated By
- BioGRID