Publication

rgr oncogene: activation by elimination of translational controls and mislocalization.

Hernandez-Munoz I, Benet M, Calero M, Jimenez M, Diaz R, Pellicer A

Previous studies have identified a novel oncogene, rgr, which has homology to the guanine nucleotide exchange factor (GEF) Ral guanine dissociation stimulator (RALGDS). To determine the mechanism of activation of rgr, the wild-type form was isolated. rgr is expressed physiologically at very low levels, due, at least in part, to a long 5'-untranslated region that contains eight AUGs, which inhibit ... [more]

Throughput

• Low Throughput

Curated By

• BioGRID