BAIT

TRPC5

PPP1R159, TRP5, RP1-68D15.2
transient receptor potential cation channel, subfamily C, member 5
Homo sapiens
PREY

STMN1

C1orf215, LAP18, Lag, OP18, PP17, PP19, PR22, SMN, RP1-125I3.5
stathmin 1
GO Process (5)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

TRPC5 is a regulator of hippocampal neurite length and growth cone morphology.

Greka A, Navarro B, Oancea E, Duggan A, Clapham DE

Growth cone motility is regulated by both fast voltage-dependent Ca2+ channels and by unknown receptor-operated Ca2+ entry mechanisms. Transient receptor potential (TRP) homomeric TRPC5 ion channels are receptor-operated, Ca2+-permeable channels predominantly expressed in the brain. Here we show that TRPC5 is expressed in growth cones of young rat hippocampal neurons. Our results indicate that TRPC5 channel subunits interact with the ... [more]

Nat. Neurosci. Aug. 01, 2003; 6(8);837-45 [Pubmed: 12858178]

Throughput

  • Low Throughput

Curated By

  • BioGRID