TFRC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- blood microparticle [IDA]
- cell surface [IDA]
- coated pit [IDA]
- cytoplasmic membrane-bounded vesicle [IDA]
- endosome [IDA]
- extracellular region [IDA]
- extracellular space [IDA]
- extracellular vesicular exosome [IDA]
- integral component of plasma membrane [TAS]
- intracellular membrane-bounded organelle [IDA]
- membrane [NAS]
- plasma membrane [TAS]
- recycling endosome [IDA]
- vesicle [IDA]
RAB17
Gene Ontology Biological Process
- GTP catabolic process [IBA, IDA]
- Rab protein signal transduction [IBA]
- cilium assembly [IMP]
- endocytic recycling [IBA, ISS]
- establishment of melanosome localization [ISS]
- filopodium assembly [ISS]
- immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor [ISS]
- intracellular protein transport [IBA]
- melanosome transport [ISS]
- regulation of dendrite development [ISS]
- regulation of endocytosis [IBA]
- regulation of filopodium assembly [IBA, ISS]
- regulation of synapse assembly [ISS]
- transcytosis [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical plasma membrane [ISS]
- basolateral plasma membrane [ISS]
- dendrite [ISS]
- early endosome [IBA]
- endocytic vesicle [IBA, IDA]
- extracellular vesicular exosome [IDA]
- intracellular [IDA]
- melanosome [ISS]
- neuronal cell body [ISS]
- plasma membrane [IBA]
- recycling endosome [ISS]
- recycling endosome membrane [IBA, ISS]
Co-localization
Interaction inferred from two proteins that co-localize in the cell by indirect immunofluorescence only when in addition, if one gene is deleted, the other protein becomes mis-localized. Also includes co-dependent association of proteins with promoter DNA in chromatin immunoprecipitation experiments.
Publication
The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes.
Macroautophagy/autophagy plays a critical role in immunity by directly degrading invading pathogens such as Group A Streptococcus (GAS), through a process that has been named xenophagy. We previously demonstrated that autophagic vacuoles directed against GAS, termed GAS-containing autophagosome-like vacuoles (GcAVs), use recycling endosomes (REs) as a membrane source. However, the precise molecular mechanism that facilitates the fusion between GcAVs and ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID