ERRFI1
Gene Ontology Biological Process
- lung alveolus development [ISO, ISS]
- lung epithelium development [ISO, ISS]
- lung vasculature development [ISO, ISS]
- negative regulation of epidermal growth factor receptor signaling pathway [ISO]
- negative regulation of epidermal growth factor-activated receptor activity [IDA, ISO, ISS]
- negative regulation of peptidyl-tyrosine phosphorylation [IDA, ISS]
- negative regulation of protein autophosphorylation [ISO, ISS]
- regulation of keratinocyte differentiation [ISO, ISS]
- skin morphogenesis [ISO, ISS]
Gene Ontology Molecular Function
YWHAG
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Chk1-mediated phosphorylation of receptor-associated late transducer at serine 250 increases its stability by stimulating its interaction with 14-3-3.
Receptor-associated late transducer (RALT) acts as a negative feedback inhibitor of ErbB receptor signaling via physical interaction with ErbB. Although RALT contains a 14-3-3 binding motif (247-RSHSGP-252), little is known about the molecular basis and significance of binding to 14-3-3. Here, we report that 14-3-3 interacts with RALT in H9c2 and COS-7 cells in a Ser-250 phosphorylation-dependent manner. An in ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID