BAIT

AHCYL1

1110034F20Rik, AA409031, AA414901, Ahcy-rs3, DCAL, Irbit
S-adenosylhomocysteine hydrolase-like 1
Mus musculus
PREY

FIP1L1

FIP1, Rhe, hFip1
factor interacting with PAPOLA and CPSF1
Glioblastoma Project
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.

Kiefer H, Mizutani A, Iemura S, Natsume T, Ando H, Kuroda Y, Mikoshiba K

IRBIT is a recently identified protein that modulates the activities of both inositol 1,4,5-triphosphate receptor and pancreas-type Na(+)/HCO(3)(-) cotransporter 1, and the multisite phosphorylation of IRBIT is required for achieving this modulatory action. Here, we report the identification of the cleavage and polyadenylation specificity factor (CPSF), which is a multi-protein complex involved in 3' processing of mRNA precursors, as an ... [more]

J. Biol. Chem. Apr. 17, 2009; 284(16);10694-705 [Pubmed: 19224921]

Throughput

  • Low Throughput

Curated By

  • BioGRID