BAIT

FIP1L1

1300019H17Rik, Rje
FIP1 like 1 (S. cerevisiae)
GO Process (1)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Mus musculus
PREY

AHCYL1

1110034F20Rik, AA409031, AA414901, Ahcy-rs3, DCAL, Irbit
S-adenosylhomocysteine hydrolase-like 1
Mus musculus

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.

Kiefer H, Mizutani A, Iemura S, Natsume T, Ando H, Kuroda Y, Mikoshiba K

IRBIT is a recently identified protein that modulates the activities of both inositol 1,4,5-triphosphate receptor and pancreas-type Na(+)/HCO(3)(-) cotransporter 1, and the multisite phosphorylation of IRBIT is required for achieving this modulatory action. Here, we report the identification of the cleavage and polyadenylation specificity factor (CPSF), which is a multi-protein complex involved in 3' processing of mRNA precursors, as an ... [more]

J. Biol. Chem. Apr. 17, 2009; 284(16);10694-705 [Pubmed: 19224921]

Throughput

  • Low Throughput

Curated By

  • BioGRID