BAIT
KIAA1429
fSAP121, MSTP054
KIAA1429
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
ATP7A
DSMAX, MK, MNK, SMAX3, RP3-465G10.1
ATPase, Cu++ transporting, alpha polypeptide
GO Process (38)
GO Function (7)
GO Component (11)
Gene Ontology Biological Process
- T-helper cell differentiation [ISS]
- blood vessel development [ISS]
- blood vessel remodeling [ISS]
- cartilage development [ISS]
- catecholamine metabolic process [ISS]
- cellular copper ion homeostasis [IMP]
- central nervous system neuron development [ISS]
- cerebellar Purkinje cell differentiation [ISS]
- collagen fibril organization [ISS]
- copper ion export [ISS]
- copper ion import [ISS]
- copper ion transport [IMP]
- detoxification of copper ion [ISS]
- dopamine metabolic process [ISS]
- elastic fiber assembly [ISS]
- elastin biosynthetic process [ISS]
- epinephrine metabolic process [ISS]
- extracellular matrix organization [ISS]
- hair follicle morphogenesis [ISS]
- ion transmembrane transport [TAS]
- locomotory behavior [ISS]
- lung alveolus development [ISS]
- mitochondrion organization [ISS]
- negative regulation of metalloenzyme activity [ISS]
- neuron projection morphogenesis [ISS]
- norepinephrine metabolic process [ISS]
- peptidyl-lysine modification [ISS]
- pigmentation [ISS]
- positive regulation of catalytic activity [ISS]
- positive regulation of metalloenzyme activity [ISS]
- positive regulation of oxidoreductase activity [IDA]
- pyramidal neuron development [ISS]
- regulation of oxidative phosphorylation [ISS]
- removal of superoxide radicals [ISS]
- serotonin metabolic process [ISS]
- skin development [ISS]
- transmembrane transport [TAS]
- tryptophan metabolic process [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation.
N6-methyladenosine (m6A) is enriched in 3'untranslated region (3'UTR) and near stop codon of mature polyadenylated mRNAs in mammalian systems and has regulatory roles in eukaryotic mRNA transcriptome switch. Significantly, the mechanism for this modification preference remains unknown, however. Herein we report a characterization of the full m6A methyltransferase complex in HeLa cells identifying METTL3/METTL14/WTAP/VIRMA/HAKAI/ZC3H13 as the key components, and we ... [more]
Cell Discov Mar. 07, 2018; 4();10 [Pubmed: 29507755]
Throughput
- High Throughput
Additional Notes
- The RNA of the 'hit' genes was identified in an RIP-seq (RNA immunoprecipitation sequencing) experiment using the 'bait' protein, VIRMA.
Curated By
- BioGRID