BAIT

ARF4

ARF2
ADP-ribosylation factor 4
Homo sapiens
PREY

APBA2

D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L
amyloid beta (A4) precursor protein-binding, family A, member 2
GO Process (1)
GO Function (1)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein.

Hill K, Li Y, Bennett M, McKay M, Zhu X, Shern J, Torre E, Lah JJ, Levey AI, Kahn RA

Coat proteins cycle between soluble and membrane-bound locations at the time of vesicle biogenesis and act to regulate the assembly of the vesicle coat that determines the specificity in cargo selection and the destination of the vesicle. A transmembrane cargo protein, an Arf GTPase, and a coat protein (e.g. COPs, APs, or GGAs) are minimal components required for budding of ... [more]

J. Biol. Chem. Sep. 19, 2003; 278(38);36032-40 [Pubmed: 12842896]

Throughput

  • Low Throughput

Curated By

  • BioGRID