BAIT
KIAA1429
fSAP121, MSTP054
KIAA1429
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
STOML2
SLP-2, HSPC108
stomatin (EPB72)-like 2
GO Process (14)
GO Function (3)
GO Component (9)
Gene Ontology Biological Process
- CD4-positive, alpha-beta T cell activation [ISS]
- T cell receptor signaling pathway [IMP]
- cellular calcium ion homeostasis [IMP]
- interleukin-2 production [ISS]
- lipid localization [ISS]
- mitochondrial ATP synthesis coupled proton transport [IMP]
- mitochondrial calcium ion transport [IMP]
- mitochondrial protein processing [ISS]
- mitochondrion organization [IMP]
- positive regulation of cardiolipin metabolic process [IMP]
- positive regulation of mitochondrial DNA replication [IMP]
- positive regulation of mitochondrial membrane potential [IMP]
- protein oligomerization [IDA]
- stress-induced mitochondrial fusion [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation.
N6-methyladenosine (m6A) is enriched in 3'untranslated region (3'UTR) and near stop codon of mature polyadenylated mRNAs in mammalian systems and has regulatory roles in eukaryotic mRNA transcriptome switch. Significantly, the mechanism for this modification preference remains unknown, however. Herein we report a characterization of the full m6A methyltransferase complex in HeLa cells identifying METTL3/METTL14/WTAP/VIRMA/HAKAI/ZC3H13 as the key components, and we ... [more]
Cell Discov Mar. 07, 2018; 4();10 [Pubmed: 29507755]
Throughput
- High Throughput
Curated By
- BioGRID