BAIT
PTPRF
BNAH2, LAR, RP5-1029K14.1
protein tyrosine phosphatase, receptor type, F
GO Process (4)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
EEF1G
EF1G, GIG35, PRO1608
eukaryotic translation elongation factor 1 gamma
GO Process (5)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
DEPDC1B coordinates de-adhesion events and cell-cycle progression at mitosis.
Cells entering mitosis become rounded, lose attachment to the substrate, and increase their cortical rigidity. Pivotal to these events is the dismantling of focal adhesions (FAs). How mitotic reshaping is linked to commitment to divide is unclear. Here, we show that DEPDC1B, a protein that accumulates in G2, coordinates de-adhesion events and cell-cycle progression at mitosis. DEPDC1B functions as an ... [more]
Dev. Cell Nov. 24, 2014; 31(4);420-33 [Pubmed: 25458010]
Throughput
- Low Throughput
Curated By
- BioGRID