BAIT
ATG16L1
APG16L, ATG16A, ATG16L, IBD10, WDR30, hCG_1817841
autophagy related 16-like 1 (S. cerevisiae)
GO Process (3)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ALB
ANALBA, FDAH, PRO0883, PRO0903, PRO1341, GIG20
albumin
GO Process (16)
GO Function (10)
GO Component (7)
Gene Ontology Biological Process
- bile acid and bile salt transport [TAS]
- bile acid metabolic process [TAS]
- blood coagulation [TAS]
- cellular response to starvation [IDA]
- hemolysis by symbiont of host erythrocytes [IDA]
- lipoprotein metabolic process [TAS]
- maintenance of mitochondrion location [IDA]
- negative regulation of apoptotic process [IDA]
- negative regulation of programmed cell death [NAS]
- platelet activation [TAS]
- platelet degranulation [TAS]
- retina homeostasis [IEP]
- small molecule metabolic process [TAS]
- sodium-independent organic anion transport [TAS]
- transmembrane transport [TAS]
- transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
ATG5 is required for B cell polarization and presentation of particulate antigens.
The involvement of macroautophagy/autophagy proteins in B-cell receptor (BCR) trafficking, although suspected, is not well understood. We show that ATG5 (autophagy related 5) contributes to BCR polarization after stimulation and internalization into LAMP1 (lysosomal-associated membrane protein 1)+ and major histocompatibility complex class II (MHC-II)+ compartments. BCR polarization is crucial in the context of immobilized antigen processing. Moreover, antigen presentation to ... [more]
Autophagy Feb. 01, 2019; 15(2);280-294 [Pubmed: 30196744]
Throughput
- High Throughput
Curated By
- BioGRID