BAIT
ATG16L1
APG16L, ATG16A, ATG16L, IBD10, WDR30, hCG_1817841
autophagy related 16-like 1 (S. cerevisiae)
GO Process (3)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GTF2H2
BTF2, BTF2P44, T-BTF2P44, TFIIH, p44
general transcription factor IIH, polypeptide 2, 44kDa
GO Process (20)
GO Function (8)
GO Component (2)
Gene Ontology Biological Process
- 7-methylguanosine mRNA capping [TAS]
- ATP catabolic process [IDA]
- DNA repair [TAS]
- G-protein coupled receptor internalization [IMP]
- gene expression [TAS]
- nucleotide-excision repair [TAS]
- nucleotide-excision repair, DNA damage removal [TAS]
- positive regulation of viral transcription [TAS]
- protein phosphorylation [IDA]
- response to UV [TAS]
- termination of RNA polymerase I transcription [TAS]
- transcription elongation from RNA polymerase I promoter [TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase I promoter [TAS]
- transcription from RNA polymerase II promoter [IDA, TAS]
- transcription initiation from RNA polymerase I promoter [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
- transcription-coupled nucleotide-excision repair [TAS]
- translation [TAS]
- viral process [TAS]
Gene Ontology Molecular Function- DNA-dependent ATPase activity [IDA]
- RNA polymerase II carboxy-terminal domain kinase activity [IDA]
- nucleic acid binding [TAS]
- protein N-terminus binding [IPI]
- protein binding [IPI]
- protein kinase activity [IDA]
- sequence-specific DNA binding transcription factor activity [NAS]
- translation factor activity, nucleic acid binding [TAS]
- DNA-dependent ATPase activity [IDA]
- RNA polymerase II carboxy-terminal domain kinase activity [IDA]
- nucleic acid binding [TAS]
- protein N-terminus binding [IPI]
- protein binding [IPI]
- protein kinase activity [IDA]
- sequence-specific DNA binding transcription factor activity [NAS]
- translation factor activity, nucleic acid binding [TAS]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
ATG5 is required for B cell polarization and presentation of particulate antigens.
The involvement of macroautophagy/autophagy proteins in B-cell receptor (BCR) trafficking, although suspected, is not well understood. We show that ATG5 (autophagy related 5) contributes to BCR polarization after stimulation and internalization into LAMP1 (lysosomal-associated membrane protein 1)+ and major histocompatibility complex class II (MHC-II)+ compartments. BCR polarization is crucial in the context of immobilized antigen processing. Moreover, antigen presentation to ... [more]
Autophagy Feb. 01, 2019; 15(2);280-294 [Pubmed: 30196744]
Throughput
- High Throughput
Curated By
- BioGRID