BAIT
ACTC1
ACTC, ASD5, CMD1R, CMH11, LVNC4
actin, alpha, cardiac muscle 1
GO Process (10)
GO Function (3)
GO Component (11)
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- actin filament-based movement [IDA]
- actin-myosin filament sliding [IMP]
- actomyosin structure organization [ISS]
- apoptotic process [ISS]
- cardiac muscle tissue morphogenesis [ISS]
- cardiac myofibril assembly [ISS]
- heart contraction [IMP]
- muscle filament sliding [TAS]
- skeletal muscle thin filament assembly [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MYO1C
MMI-beta, MMIb, NMI, myr2
myosin IC
GO Process (10)
GO Function (2)
GO Component (14)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- innate immune response [TAS]
- membrane organization [TAS]
- positive regulation of cell migration [IMP]
- positive regulation of cell migration by vascular endothelial growth factor signaling pathway [IMP]
- positive regulation of protein targeting to membrane [IMP]
- positive regulation of vascular endothelial growth factor signaling pathway [IMP]
- protein targeting [IDA]
- protein targeting to membrane [IDA]
- regulation of tight junction assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basal plasma membrane [IDA]
- cytoplasm [IDA]
- cytosol [TAS]
- extracellular vesicular exosome [IDA]
- filamentous actin [IDA]
- lateral plasma membrane [IDA]
- membrane [IDA]
- membrane raft [IDA]
- microvillus [IDA]
- mitochondrion [IDA]
- nucleoplasm [IDA]
- plasma membrane [IDA]
- stress fiber [IDA]
- unconventional myosin complex [TAS]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.
In addition to its essential functions within the cytoskeleton, actin also localizes to the cell nucleus, where it is linked to many important nuclear processes from gene expression to maintenance of genomic integrity. However, the molecular mechanisms by which actin operates in the nucleus remain poorly understood. Here, we have used two complementary mass spectrometry (MS) techniques, AP-MS and BioID, ... [more]
J. Cell. Sci. Apr. 17, 2019; 132(8); [Pubmed: 30890647]
Throughput
- High Throughput
Curated By
- BioGRID