BAIT

KCNC2

KV3.2
potassium voltage-gated channel, Shaw-related subfamily, member 2
UPS Project
Homo sapiens
PREY

KCNC1

KV3.1, KV4, NGK2
potassium voltage-gated channel, Shaw-related subfamily, member 1
UPS Project
GO Process (3)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Kv3.1b is a novel component of CNS nodes.

Devaux J, Alcaraz G, Grinspan J, Bennett V, Joho R, Crest M, Scherer SS

We herein demonstrate that Kv3.1b subunits are present at nodes of Ranvier in the CNS of both rats and mice. Kv3.1b colocalizes with voltage-gated Na+ channels in a subset of nodes in the spinal cord, particularly those of large myelinated axons. Kv3.1b is abundantly expressed in the gray matter of the spinal cord, but does not colocalize with Na+ channels ... [more]

J. Neurosci. Jun. 01, 2003; 23(11);4509-18 [Pubmed: 12805291]

Throughput

  • Low Throughput

Curated By

  • BioGRID