BAIT
EMP2
NPHS10, XMP
epithelial membrane protein 2
GO Process (25)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- T cell mediated cytotoxicity [ISS]
- actin filament organization [IDA]
- actin-mediated cell contraction [IDA]
- activation of protein kinase activity [IDA]
- bleb assembly [IDA]
- blood vessel endothelial cell migration [IDA]
- caveola assembly [ISS]
- cell adhesion [IDA]
- cell death [IDA]
- cell migration [IDA]
- cell proliferation [IDA]
- cell-matrix adhesion [IDA]
- early endosome to late endosome transport [ISS]
- embryo implantation [IMP]
- membrane raft assembly [ISS]
- positive regulation of cell proliferation [IMP]
- positive regulation of cell-matrix adhesion [IDA]
- positive regulation of integrin-mediated signaling pathway [IDA]
- protein localization to cell surface [IMP]
- protein localization to plasma membrane [ISS]
- regulation of angiogenesis [IDA, IMP]
- regulation of endothelial cell migration [IDA]
- regulation of glomerular filtration [IDA]
- regulation of kinase activity [IDA]
- regulation of vasculogenesis [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
EPM2AIP1
My007
EPM2A (laforin) interacting protein 1
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of a novel protein interacting with laforin, the EPM2a progressive myoclonus epilepsy gene product.
We have identified an interacting partner protein (encoded by the human EPM2AIP1 gene (approved symbol)) for laforin, the product of the EPM2A gene, which is mutated in an autosomal recessive form of adolescent progressive myoclonus epilepsy. The EPM2AIP1 gene was identified in a screen for laforin-interacting proteins with a human brain cDNA library using the yeast two-hybrid system. The specificity ... [more]
Genomics Jun. 01, 2003; 81(6);579-87 [Pubmed: 12782127]
Throughput
- Low Throughput
Curated By
- BioGRID