ERAS
PIK3CG
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IDA]
- T cell activation [TAS]
- T cell chemotaxis [TAS]
- T cell proliferation [TAS]
- adaptive immune response [TAS]
- blood coagulation [TAS]
- cytokine production [TAS]
- dendritic cell chemotaxis [TAS]
- inflammatory response [TAS]
- innate immune response [TAS]
- mast cell degranulation [TAS]
- natural killer cell chemotaxis [TAS]
- negative regulation of cardiac muscle contraction [TAS]
- neutrophil chemotaxis [TAS]
- neutrophil extravasation [TAS]
- phosphatidylinositol 3-kinase signaling [IDA, TAS]
- phosphatidylinositol biosynthetic process [TAS]
- phospholipid metabolic process [TAS]
- platelet activation [TAS]
- platelet aggregation [TAS]
- positive regulation of MAP kinase activity [IDA]
- positive regulation of protein kinase B signaling [IDA]
- regulation of cell adhesion mediated by integrin [TAS]
- respiratory burst involved in defense response [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells.
Embryonic stem (ES) cells are pluripotent cells derived from early mammalian embryos. Their immortality and rapid growth make them attractive sources for stem cell therapies; however, they produce tumours (teratomas) when transplanted, which could preclude their therapeutic usage. Why ES cells, which lack chromosomal abnormalities, possess tumour-like properties is largely unknown. Here we show that mouse ES cells specifically express ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID