MOG-5
Gene Ontology Biological Process
- apoptotic process [IMP]
- developmental growth [IMP]
- embryo development ending in birth or egg hatching [IMP]
- embryonic body morphogenesis [IMP]
- feminization of hermaphroditic germ-line [IMP]
- germ cell development [IMP]
- locomotion [IMP]
- molting cycle, collagen and cuticulin-based cuticle [IMP]
- nematode larval development [IMP]
- regulation of cell proliferation [IMP]
- regulation of meiosis [IMP]
- reproduction [IMP]
Gene Ontology Molecular Function
SOS-1
Gene Ontology Biological Process
- body morphogenesis [IMP]
- cell migration [IMP]
- embryo development [IMP]
- embryo development ending in birth or egg hatching [IMP]
- female gamete generation [IMP]
- oviposition [IMP]
- positive regulation of Ras GTPase activity [ISS]
- positive regulation of vulval development [IGI]
- reproduction [IMP]
- secretion by cell [IMP]
Gene Ontology Molecular Function
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
EPIC: software toolkit for elution profile-based inference of protein complexes.
Protein complexes are key macromolecular machines of the cell, but their description remains incomplete. We and others previously reported an experimental strategy for global characterization of native protein assemblies based on chromatographic fractionation of biological extracts coupled to precision mass spectrometry analysis (chromatographic fractionation-mass spectrometry, CF-MS), but the resulting data are challenging to process and interpret. Here, we describe EPIC ... [more]
Quantitative Score
- 0.525 [Confidence Score]
Throughput
- High Throughput
Additional Notes
- High confidence protein interactions have an EPIC PPI score >= 0.5
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SOS-1 MOG-5 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | 3.0556 | BioGRID | 466313 |
Curated By
- BioGRID