BAIT
PHB
HEL-215, HEL-S-54e, PHB1
prohibitin
GO Process (15)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- cellular response to interleukin-6 [IDA]
- histone deacetylation [IDA]
- negative regulation of androgen receptor signaling pathway [IDA, IMP]
- negative regulation of cell growth [IMP]
- negative regulation of cell proliferation [IMP]
- negative regulation of glucocorticoid receptor signaling pathway [IDA]
- negative regulation of transcription by competitive promoter binding [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA, IMP]
- osteoblast differentiation [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- progesterone receptor signaling pathway [IDA]
- regulation of apoptotic process [TAS]
- regulation of transcription, DNA-templated [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RAB33B
SMC2
RAB33B, member RAS oncogene family
GO Process (12)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- GTP catabolic process [IBA, IMP]
- Rab protein signal transduction [IBA]
- intra-Golgi vesicle-mediated transport [IMP]
- intracellular protein transport [IBA]
- negative regulation of constitutive secretory pathway [IMP]
- protein targeting to Golgi [IGI, IMP]
- regulation of Golgi organization [IMP]
- regulation of autophagic vacuole assembly [IBA, ISS]
- regulation of cell growth [IMP]
- regulation of epithelial cell proliferation [IMP]
- regulation of retrograde vesicle-mediated transport, Golgi to ER [IMP]
- skeletal system morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.
... [more]
J Mol Cell Biol Dec. 01, 2015; 8(3);282-5 [Pubmed: 27025967]
Throughput
- High Throughput
Curated By
- BioGRID