BAIT

SLC31A1

COPT1, CTR1, RP11-110L1.1
solute carrier family 31 (copper transporter), member 1
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens
PREY

SLC31A1

COPT1, CTR1, RP11-110L1.1
solute carrier family 31 (copper transporter), member 1
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The N-terminus of the human copper transporter 1 (hCTR1) is localized extracellularly, and interacts with itself.

Klomp AE, Juijn JA, van der Gun LT, van den Berg IE, Berger R, Klomp LW

We have used indirect immunofluorescense studies and glycosylation-site insertion and deletion mapping to characterize the topology of human copper transporter 1 (hCTR1), the putative human high-affinity copper-import protein. Both approaches indicated that hCTR1 contains three transmembrane domains and that the N-terminus of hCTR1, which contains several putative copper-binding sites, is localized extracellularly, whereas the C-terminus is exposed to the cytosol. ... [more]

Biochem. J. Mar. 15, 2003; 370(0);881-9 [Pubmed: 12466020]

Throughput

  • Low Throughput

Curated By

  • BioGRID