BAIT
SLC31A1
COPT1, CTR1, RP11-110L1.1
solute carrier family 31 (copper transporter), member 1
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC31A1
COPT1, CTR1, RP11-110L1.1
solute carrier family 31 (copper transporter), member 1
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
The N-terminus of the human copper transporter 1 (hCTR1) is localized extracellularly, and interacts with itself.
We have used indirect immunofluorescense studies and glycosylation-site insertion and deletion mapping to characterize the topology of human copper transporter 1 (hCTR1), the putative human high-affinity copper-import protein. Both approaches indicated that hCTR1 contains three transmembrane domains and that the N-terminus of hCTR1, which contains several putative copper-binding sites, is localized extracellularly, whereas the C-terminus is exposed to the cytosol. ... [more]
Biochem. J. Mar. 15, 2003; 370(0);881-9 [Pubmed: 12466020]
Throughput
- Low Throughput
Curated By
- BioGRID